FASCIN CONTROLS METASTATIC COLONIZATION AND MITOCHONDRIAL OXIDATIVE PHOSPHORYLATION BY REMODELING MITOCHONDRIAL ACTIN FILAMENTS

Fascin Controls Metastatic Colonization and Mitochondrial Oxidative Phosphorylation by Remodeling Mitochondrial Actin Filaments

Summary: The deregulation of the actin cytoskeleton has Proximity Automation been extensively studied in metastatic dissemination.However, the post-dissemination role of the actin cytoskeleton dysregulation is poorly understood.Here, we report that fascin, an actin-bundling protein, promotes lung cancer metastatic colonization by augmenting metabol

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